منابع مشابه
hsp90: Twist and Fold
Molecular chaperones are cellular machines that facilitate protein folding. The crystal structures of HtpG, the Escherichia coli homolog of hsp90, reported in this issue (Shiau et al., 2006) together with the recently published structures of an hsp90-cochaperone complex (Ali et al., 2006) and an hsp90-client protein complex (Vaughan et al., 2006), reveal exciting insights into the hsp90 reactio...
متن کاملMaterials for semiconductor devices that can bend , fold , twist , and stretch
© 2014 Materials Research Society MRS BULLETIN • VOLUME 39 • JUNE 2014 • www.mrs.org/bulletin Introduction Research discoveries over the last 10 years provide routes to advanced electronic and optoelectronic systems that offer linear elastic mechanical responses to large-strain deformations. 1 , 2 Such devices can be bent, twisted, folded, stretched, and conformally wrapped onto arbitrarily cur...
متن کاملTwist-Stretch Elasticity of DNA
The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally-constrained single molecules give the first direct measurement of this important material parameter. We extract its value from a recent experiment of Strick, et al. and find rough agreement with an independent experimental estima...
متن کاملDirect Determination of DNA Twist-Stretch Coupling
Direct Determination of DNA Twist-Stretch Coupling Randall D. Kamien, Tom C. Lubensky, Philip Nelson, and Corey S. O'Hern Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104 USA The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionallyconstrained sing...
متن کاملSequence-dependent twist-stretch coupling in DNA.
Recent single-molecule micromanipulation experiments on DNA subject to small distortion revealed positive coupling between DNA stretching and twisting--for instance, DNA elongates when overtwisted. Here we propose a method to calculate the twist-stretch coupling constant specific to a DNA fragment of a given sequence. The method employs a sequence-dependent dinucleotide force field and is based...
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ژورنال
عنوان ژورنال: Nature
سال: 1989
ISSN: 0028-0836,1476-4687
DOI: 10.1038/341285a0